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Vitaflavan
> What is vitaflavan® ?
vitaflavan® is the commercial name given to a health ingredient extracted from white grape seeds from south-west France. vitaflavan® contains a guaranteed level of oligomeric procyanidins (OPC), the active ingredient that is beneficial for health. Research carried out on OPC and particularly on vitaflavan®, has demonstrated their multiple biological effects: antioxidant, vascular protection, skin protection, and slimming.
vitaflavan® is a health product that can be incorporated into dietary supplements, functional foods, or cosmetics.
> What is the difference between vitaflavan® and oligopin® ?
vitaflavan® is extracted from white grape seeds whereas oligopin® is extracted from French maritime pine bark. Both products have a guaranteed content in oligomeric procyanidins or OPC.
However, their proportion of monomers, dimers, trimers and tetramers are slightly different.
The various studies carried out on these products demonstrate that oligopin® and vitaflavan® have antioxidant, anti-inflammatory and vascular protection properties.
oligopin® is also widely used for its properties in beauty care and skin protection: cell-ageing prevention, elastin and collagen protection, depigmentation, stimulation of microcirculation.
vitaflavan® is used for its slimming properties: increase in energy expenditure, stimulation of lipolysis.
> Is vitaflavan® bioavailable ?
vitaflavan® is a bioavailable product. Indeed, vitaflavan® has a guaranteed high content of short catechin and epicatechin oligomers. Oligomers are small molecules that are easily absorbed and have multiple biological actions.
Polymers have a higher molecular weight and are not easily absorbed. As a result, they have very weak biological action. In some cases, they may even have an anti-nutritional effect by bindind to proteins and enzymes. That is why DRT eliminates polymers despite their abundant presence in health ingredients that have not been sufficiently purified.
> What is the difference between catechin and OPC ?
OPC, or oligomeric procyanidins, are formed from an identical pattern, called catechin or epicatechin, repeated 2, 3, 4 or 5 times.
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Molecules formed from more than 5 repetitions are called polymers, which have a higher molecular weight, are absorbed very little and therefore have very weak biological activity.
Catechins are mainly found in green tea, whereas oligomeric procyanidins are mainly extracted from grape seeds and maritime pine bark. Catechin do not have the same affinity for specific biological site as oligomeric procyanidins.
> Is it necessary to continue taking vitamins whilst taking vitaflavan® ?
vitaflavan® is a health ingredient that delivers bioavailable OPC. OPC’s antioxidant action is stronger than that of vitamins C. Moreover, OPC remain active in hydrosoluble media. OPC can thus protect cells globally (cytoplasma, plasma membrane) against attacks from free radicals. In any case, the OPC in vitaflavan® and vitamins act in synergy so taking vitamins and OPC together increases each molecule’s effect.
vitaflavan® does not replace vitamins but supplements them and reinforces their effect.
> Are there any contraindications to the use of vitaflavan® ?
Given the lack of sufficient scientific data we do not recommend vitaflavan® for children under 12. The same recommendation applies to pregnant women or nursing mothers. We recommend seeking the advice of your pharmacist or dietician.
> Why is vitaflavan® not an ordinary grape seed extract ?
vitaflavan® is extracted from white grape seeds from the south west of France.
vitaflavan® is a health ingredient with guaranteed OPC content (more than 75%).
vitaflavan® is recognized for its purity and strict chemical characterisation. vitaflavan® has a guaranteed high content in short catechin and epicatechin oligomers. These molecules are small and therefore easily absorbed by the intestinal barrier. This makes vitaflavan® bioavailable. Once in the blood stream, OPC have beneficial effects on their various targets: vascular system, skin, adipose cells…
> Should you eat white grapes to have the beneficial effects of vitaflavan® ?
vitaflavan® is good for your health because of its high OPC content. Despite their abundance in nature, our diet provides us with very few OPC.
In fact, OPC are found in the peel or skins of fruits and vegetables, or in the cuticles covering seeds or cereals. The extraction of OPC requires very special conditions that do not occur during digestion. In order to benefit from the full biological action of vitaflavan®, it is recommended to take 60 to 120 mg per day. To absorb an equivalent amount of OPC as that provided in 120 mg of vitaflavan®, you should theoretically eat 500 g of grapes per day. Even then, the OPC contained in the fruit will not be very highly absorbed.
> Where can I find vitaflavan® ?
vitaflavan® can be found in dietary supplements, functional foods, and cosmetics. Oligomeric procyanidins, or OPC are usually included in health formulas in the following areas: antioxidants, sun protection, vascular protection, draining, relief for tired legs, slimming, cardiovascular health.
> What is the daily recommended dose of vitaflavan® ?
It is recommended to take between 60 and 120 mg of vitaflavan® daily to obtain the maximum biological effects. Depending on the type of product, capsule or food, the daily dosage of vitaflavan® can be taken once or divided into several intakes throughout the day.
Depending on the desired effect, duration of vitaflavan® treatment will be variable, with a minimum of one month, although it can be taken for longer periods and repeated several times a year. In any case, it is important to refer to the recommended dosage indicated on the product itself, and to seek the advice of a pharmacist or dietician.
> Does vitaflavan® help you slim ?
vitaflavan®, taken alone or in combination with other dieting substances, is an effective slimming aid. However, dietary supplements or functional foods for slimming purposes should be taken whilst following a calorie controlled diet and pursuing even moderate physical exercise in order to succeed in losing body weight.
Nonetheless, vitaflavan® will help as a stimulant to break down stored fat. Incorporated into cosmetics, vitaflavan® can improve your skin’s appearance if you have orange peel or cellulite.
For a full slimming effect, vitaflavan® can be combined with green tea extracts, coffee, conjugated linoleic acid, and cinnamon.
> Do I need to take vitaflavan® ?
vitaflavan® is recommended for the following :
- Slimming course, cellulite, orange-peel skin, dimples
- Sun exposure
- Dull complexion
- Skin ageing
- Antioxidant treatment
- Stress
- Smokers
- Intensive sport
> How can I be sure that a product contains vitaflavan® ?
To be sure that a product contains vitaflavan® you must read the list of ingredients. If “vitaflavan®” appears, then the product has been made with our ingredient.
Other terms may be used, but do not guarantee the presence of vitaflavan® in the product :
- “Extract of white grape seeds”
- “OPC from white grape seed”
- “OPC”
- “Polyphenols from white grape seed”
- “Oligomeric procyanidins”
- “Vitis vinifera seed extract”


